This collection is composed primarily of correspondence between M. Carey Thomas and her nephew, Dr. Henry M. Thomas, Jr. These letters written by M. Carey Thomas and the (carbon copies of the) replies of H. M. Thomas are filled with news of their travels, their households, and their work, as well as news of their family and friends, many of whom were connected with Johns Hopkins. Many of the letters also contain personal medical information that M. Carey Thomas provided to her nephew, who also served as her physician. He consulted frequently with his uncle, Dr. Simon Flexner, regarding his aunt's health; their correspondence is also included. The collection also contains clippings about M. Carey Thomas and Bryn Mawr as well as reprints of her publications. Also included are correspondence and records regarding the maintenance of The Mary E. Garrett Memorial Room in the Johns Hopkins Hospital.