The John W. Littlefield Collection spans his entire career at Johns Hopkins. It consists of correspondence, committee files, reprints, administrative records, financial records, and faculty planning materials. A series of historical reprints includes articles by Edwards Park, Joseph Brennemann, and Lawson Wilkins. There are files with information on typhoid, pneumonia, and salmonella infections. A file on procedures (c.1950s) for the premature nursery of the Harriet Lane Home is also included